Division of Mikrobiologie

Professor of the Microbiology department


Prof. Dr. Nicole Frankenberg-Dinkel

Department Microbiology; TU Kaiserslautern
Gebäude 23 , Raum 195

Tel.: +49 631 +49 (0)631 205 2353
Fax: +49 631 +49 (0)631 205 3799
E-Mail: nfranken[a]bio.uni-kl.de

Consultation hours by appointment.

Curriculum Vitae

1990-1996Studies of Biology at the Universities of Regensburg, Germany and Boulder, Colorado, USA
1996 Diploma thesis at the University of Regensburg; Supervisor: Günter Hauska
1996-1999PhD in Biochemistry at the University of Freiburg, Germany; Supervisor: Dieter Jahn
1999-2002Postdoc at the Department of Molecular and Cellular Biology, University of California at Davis, USA; Supervisor: J. Clark Lagarias
2003-2005Group leader within the Emmy-Noether-Program (DFG) at the Technical University Braunschweig, Germany
2006-2014 W2-Professor for Physiology of Microorganisms at the Ruhr University Bochum, Germany
Since 09/2014 W3-Professor for Microbiology at the Technical University Kaiserslautern, Germany

Major Research Interests

Our research group has a broad interest in how microorganisms perceive their environment and adapt to changing conditions. For these investigations, we use different model organisms: phototrophic cyanobacteria, which produce energy with the help of light, the opportunistic pathogenic bacterium Pseudomonas aeruginosa, which is a serious pathogen through the formation of biofilms, as well as Methanosarcina acetivorans, a representative of the Archaea, which carry out so-called methanogenesis under exclusion of oxygen. Details about our research interests can be found here.

Selected Publications

Fiege, K. and Frankenberg-Dinkel, N. (2019) Thiol-based redox sensing in the methyltransferase associated sensor kinase RdmS in Methanosarcina acetivorans. Environ. Microbiol. 21(5),1597-1610.


Bedrunka, P., Olbrisch, F., Rüger, M., Zehner, S. and Frankenberg-Dinkel, N. (2018) Nitric oxide controls c-di-GMP turnover in Dinoroseobacter shibae. Microbiol. 164 (11), 1405-1415.


Ledermann, B., Schwan, M., Sommerkamp, J.A., Hofmann, E., Béjà, O. and Frankenberg-Dinkel, N. (2018) Evolution and molecular mechanism of four-electron reduction ferredoxin-dependent bilin reductases from oceanic phages. FEBS Journal 285(2), 339-356. 


Gasper, R., Schwach, J., Hartmann, J., Holtkamp, A., Wiethaus, J., Riedel, N., Hofmann, E. and Frankenberg-Dinkel, N. (2017) Auxiliary metabolic genes - Distinct features of cyanophage-encoded T-type phycobiliprotein lyase θCpeT J. Biol. Chem. 292(8), 3089-3098.


Li, Y., Heine, S., Entian, M., Sauer, K. and Frankenberg-Dinkel, N. (2013) NO-induced biofilm dispersion in Pseudomonas aeruginosa is mediated by an MHYT-domain coupled phosphodiesterase. J. Bacteriol. 195(16), 3531-3542.

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