Fachgebiet Molecular Genetics of Eukaryotes


Trösch R, Ries F, Westrich LD, Gao Y, Herkt C, Hoppstädter J, Heck-Roth J, Mustas M, Scheuring D, Choquet Y, Räschle M, Zoschke R and Willmund F. Fast and global reorganization of the chloroplast protein biogenesis network during heat acclimation. The Plant Cell, 34(3), 1075-1099. https://doi.org/10.1093/plcell/koab317


Chunduri N, Menges P, Zhang X, Wieland A, Gotsmann V, Mardin B, Buccitelli C, Korbel J, Willmund F, Kschischo M, Räschle M and Storchova Z. Systems approaches identify the consequences of monosomy in somatic human cells. Nature Communications (2021), 12 (5576). DOI: https://doi.org/10.1038/s41467-021-25288-x. Preprint at bioRxiv doi.org/10.1101/2021.02.22.432226

Westrich LD, Gotsmann VL, Herkt C, Ries F, Kazek T, Trösch R, Armbruster L, Mühlenbeck JS, Ramundo S, Nickelsen J, Finkemeier I, Wirtz M, Storchová Z, Raeschle M and Willmund F. The versatile interactome of chloroplast ribosomes revealed by affinity purification mass spectrometry. Nucleic Acid Research 49(19) 400-415, doi:10.1093/nar/gkaa1192

Kleine T, Naegele T, Neuhaus E, Schmitz-Linneweber C, Fernie A, Geigenberger P, Grimm B, Kaufmann K, Klipp E, Meurer J, Möhlmann T, Mühlhaus T, Naranjo B, Nickelsen J, Richter AS, Ruwe H, Schroda M, Schwenkert S, Trentmann O, Willmund F, Zoschke R and Leister D. Acclimation in plants - the Green Hub consortium. Plant Journal, doi: 10.1111/tpj.15144 (review).



Ries F, Herkt C and Willmund F. Co-Translational Protein Folding and Sorting in Chloroplasts. Plants. Invited review. doi: 10.3390/plants9020214

Theis J, Niemeyer J, Schmollinger S, Ries F, Rütgers M, Gupta TK, Sommer F, Muranaka LS, Venn, B, Schulz-Raffelt M, Willmund F, Engel B and Schroda M. VIPP2 interacts with VIPP1 and HSP22E/F at chloroplast membranes and modulates a retrograde signal for HSP22E/F gene expression. Plant Cell and Envir. Jan 29. doi: 10.111/pce.13732.

Leisen T, Bietz F,  Werner J, Wegner A, Schaffrath U, Scheuring D, Willmund F, Mosbach A, Scalliet G and Hahn M. CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient maker-free and multiple genome editing in Botrytis cinerea. PLoS Pathogens, Aug 17, doi.org/10.1371/journal.ppat.1008326. Preprint at bioRxiv doi: 10.1101/2019.12.12.874503



Westrich LD,Gotsmann VL, Herkt C, Ries F, Kazek T, Trösch R, Ramundo S, Nickelsen J, Armbruster L, Wirtz M, Storchova Z, Raeschle M and Willmund F. The proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network. bioRxiv doi: 10.1101/2019.12.12.874503


Westrich LD, Gotsmann VL and Willmund F. Chloroplasten-Proteinbiogenese: angepasst an das phototrophe Leben. BIOspektrum, 25(2), 127-131. Doi: 10.1007/s12268-019-1018-x 131. Read at Online First


Rohr M, Ries F, Herkt C, Gotsmann VL, Westrich, LD, Gries K, Trösch, R, Christmann J, Chaux-Jukic F, Jung M, Zimmer D, Mühlhaus T, Sommer F, Schroda M, Keller S, Möhlmann T, and Willmund F. The role of plastidic trigger factor serving protein biogenesis in green algae and land plants. Plant Physiology,  March 179(3):1093-1110. Open Access:  doi: 10.1104/pp.18.01252.

Trösch R and Willmund F. The conserved theme of ribosome hibernation – from bacteria to chloroplasts of plants. Biological Chemistry, Feb 1. pii: /j/bchm.ahead-of-print/hsz-2018-0436/hsz-2018-0436.xml. Open Access: doi: 10.1515/hsz-2018-0436.




Crozet P*, Navarro F*, Willmund F*, Mehrshahi P*, Bakowski K, Lauersen K, Pérez-Pérez ME, Auroy-Tarago P, Gorchs A, Sauret-Gueto S, Niemeyer J, Spaniol B, Westrich L, Theis J, Trösch R, Vavitsas K, Baier T, de Carpentier F, Danon A, Henri J, Marchand CH, de Mia M, Sarkissian K, Baulcombe D, Peltier G, Crespo JL, Kruse O, Jensen PE, Schroda M, Smith AG and Lemaire SD. Birth of a photosynthetic chassis: a MoClo toolkit enabling synthetic biology in the microalga Chlamydomonas reinhardtii. ACS Synthetic Biology (2018), Sep; 7(9). 2074-2086 

*these authors contributed equally.



Trösch R, Barahimipour R, Gao Y, Badillo Corona JA, Gotsmann VL, Zimmer D, Mühlhaus T, Zoschke R and Willmund F. Commonalities and differences of chloroplast translation in a green alga and land plants. Nature Plants (2018), Aug; 4: 564-575, Get PDF here 




Rütgers M, Muranaka LS, Mühlhaus T, Sommer F, Thoms S, Schurig J, Willmund F, Schulz-Raffelt M, Schroda M. Substrates of the chloroplast small heat shock proteins 22E/F point to thermolability as a regulative switch for heat acclimation in Chlamydomonas reinhardtii. Plant Mol Biol (2017), Dec;95(6):579-591. doi: 10.1007/s11103-017-0672-y


Ries F, Carius Y, Rohr M, Gries K, Keller S, Lancaster CRD, Willmund F. Structural and molecular comparison of bacterial and eukaryotic trigger factors. Sci Rep. (2017), Sep 6;7(1):10680. Open Access: doi: 10.1038/s41598-017-10625-2.


Rütgers M, Muranaka LS, Schulz-Raffelt M, Thoms S, Schurig J, Willmund F, Schroda M. Not changes in membrane fluidity but proteotoxic stress triggers heat shock protein expression in Chlamydomonas reinhardtii. Plant Cell Environ  (2017), Dec;40(12): 2987-3001.




Trösch R, Mühlhaus R, Schroda M, and Willmund F. ATP-dependent molecular chaperones in plastids - more complex than expected. Biochim Biophys Acta (2015), Sep;1847(9):872-88. Epub 2015 Jan 14. Review.




Neef DW, Jaeger A, Gomez-Pastor R, Willmund F, Frydman J and Thiele DJ. A direct regulatory interaction between chaperonin TRiC and stress responsive transcription factor HSF1. Cell Rep (2014), 9(3):955-966.


Trösch R, Schroda M and Willmund F. Molecular Chaperone Functions in Plastids. PLASTID BIOLOGY. Advances in Plant Biology (2014), Vol. 5:325-358. 




Pechmann S*, Willmund F*, Frydman J. The ribosome as a hub for protein quality control. Mol Cell (2013), 49: 411-21 *Authors contributed equally


Willmund F, del Alamo M, Pechmann S, Chen T, Albanèse V, Dammer EB, Peng J, Frydman J. The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell (2013), 152: 196-209


Before 2013

Zum Seitenanfang