Fachgebiet Phytopathologie

2022

Steentjes MBF, Herrera Valderrama AL, Fouillen L, Bahammou D, Leisen T, Albert I, Nürnberger T, Hahn M, Mongrand S, Scholten O, van Kan JAL (2022) Cytotoxic activity of Nep1-like proteins on monocots. New Phytol. doi:10.1111/nph.18146 

Kuang L, Chen S, Guo Y, Scheuring D, Flaishman MA, Ma M (2022) Proteome analysis of vacuoles isolated from fig (Ficus carica L.) flesh during fruit development. Plant Cell Physiol. pcac039, doi: 10.1093/pcp/pcac039

Leisen T, Werner J, Pattar P, Ymeri E, Sommer F, Schroda M, Scheuring D, Hahn M (2022) Multiple knockout mutants reveal a high redundancy of phytotoxic compounds contributing to necrotrophic pathogenesis of Botrytis cinerea.  Plos Pathogens doi :10.1371/journal.ppat.1010367


2021

Trösch R, Ries F, Westrich  LD,  Gao Y, Herkt  C, Hoppstädter J, Heck-Roth J, Mustas M, Scheuring D, Choquet Y, Räschle M, Zoschke R,  Willmund, F (2021) Fast and global reorganization of the chloroplast protein biogenesis network during heat acclimation. Plant Cell, koab317, https://doi.org/10.1093/plcell/koab317

Wegner A, Wirtz L, Leisen T, Hahn M, Schaffrath U (2021) Fenhexamid - an efficient and inexpensive fungicide for selection of Magnaporthe oryzae transformants. Eur. J. Plant Pathol. 162, 697–707 https://doi.org/10.1007/s10658-021-02432-3 

Valifard M, LeHir R, Müller J, Scheuring D, Neuhaus HE, Pommerrenig B (2021) The vacuolar fructose transporter SWEET17 is critical for Arabidopsis root development and drought tolerance. Plant Phys., kiab436, https://doi.org/10.1093/plphys/kiab436

Porquier A, Tisserant C, Salinas F, Glassl C, Wange L, Enard W, Hauser A, Hahn M, Weiberg A (2021) Retrotransposons as pathogenicity factors of the plant pathogenic fungus Botrytis cinerea. Genome Biol. 22: 225 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365987/ 

Hickl D*, Drews F*, Girke C, Zimmer D, Mühlhaus T, Hauth J, Nordström K, Trentmann O, Neuhaus HE, Scheuring D, Fehlmann T, Keller A, Simon M, Möhlmann T (2021) Differential degradation of RNA species by autophagy related pathways in Arabidopsis. J. Exp. Bot., 72, 6867-6881 doi: 10.1093/jxb/erab321
*authors contributed equally

Schurig J, Ipach U, Helmstaetter B, Kling L, Hahn M, Trapp O, Winterhagen P (2021) Selected genotypes with the genetic background of Vitis aestivalis and Vitis labrusca are resistant to Xiphinema index. Plant Dis. 105, 4132-4137 doi: 10.1094/PDIS-12-20-2716-RE

Schurig J, Ipach U, Hahn M, Winterhagen P (2021) Evaluating nematode resistance of grapevine rootstocks based on Xiphinema index reproduction rates in a fast screening assay. Eur. J. Plant Pathol 160, 233-238 doi: 10.1007/s10658-021-02227-6

Hahn M, Scalliet G (2021) One cut to change them all: CRISPR/Cas, a groundbreaking tool for genome editing in Botrytis cinerea and other fungal plant pathogens. Phytopathology 111, 474-477doi: 10.1094/PHYTO-09-20-0379-PER

Minina EA, Scheuring D, Askani J, Krueger F, Schumacher K (2021) Light at the end of the tunnel: FRAP assay reveals that plant vacuoles start as a tubular network. bioRxiv https://www.biorxiv.org/content/10.1101/2021.05.13.444058v1.abstract

Niemeyer J, Scheuring D, Oestreicher J, Morgan B, Schroda M (2021) Real-time monitoring of subcellular H2O2 distribution in Chlamydomonas reinhardtii. Plant Cell, koab176 doi: 10.1093/plcell/koab176

Kaiser S, Eisele S, Scheuring D (2021) Vacuolar occupancy is crucial for cell elongation and growth regardless of the underlying mechanism. Plant Signal. Behav. 16, 8 https://doi.org/10.1080/15592324.2021.1922796

Plesken C, Pattar P, Reiss R, Naoshin Noor Z, Zhang L, Klug K, Huettel B, Hahn M (2021) Genetic diversity of Botrytis cinerea revealed by multilocus sequencing, and identification of B. cinerea populations showing genetic isolation and distinct host adaptation. Frontiers in Plant Science, section Plant Pathogen Interactions 12, 765 doi 10.3389/fpls.2021.663027

Klionsky DJ et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 8, 1-382 doi: 10.1080/15548627.2020.1797280

Hickl D, Scheuring D, Möhlmann T (2021) CTP-Synthase 2 from Arabidopsis thaliana is required for complete embryo development. Front. Plant Sci. 15, 510 doi: 10.3389/fpls.2021.652434

2020

Jeblick T, Leisen T, Steidele CE, Mueller J, Mahler F, Sommer F, Keller S, Hueckelhoven R, Hahn M, Scheuring, D (2020) The secreted hypersensitive response inducing protein 1 from Botrytis cinerea displays non-canonical PAMP-activity. bioRxiv doi: 10.1101/2020.12.16.423131

Leisen T, Bietz F, Werner J, Wegner A, Schaffrath U, Scheuring D, Willmund F, Mosbach A, Scalliet G, Hahn M (2020) CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea. PLOS Pathogens 16(8): e1008326 https://doi.org/10.1371/journal.ppat.1008326

Scheuring D, Kleine-Vehn J (2020). On the discovery of an endomembrane compartment in plants. Proc. Natl. Acad. Sci. USA 117, 10623-10624 doi: 10.1073/pnas.2006766117

Kaiser S, Scheuring D (2020) To lead or to follow: Contribution of the plant vacuole to cell growth. Front. Plant Sci. 11, 553 https://doi.org/10.3389/fpls.2020.00553

    Ruano G, Scheuring D (2020) Plant cells under attack: Unconventional endomembrane trafficking during plant defens. Plants 2020, 9, 389  doi: 10.3390/plants9030389

    2019

    Kaiser S, Eisa A, Kleine-Vehn J, Scheuring D (2019) NET4 modulates the compactness of vacuoles in Arabidopsis thaliana. Int. J. Mol. Sci. 20, 4752 doi: 10.3390/ijms20194752

    Fan F, Hahn M, Li G-Q, Lin Y, Luo C-X (2019) Rapid detection of benzimidazole resistance in Botrytis cinerea by loop-mediated isothermal amplification. Phytopathol. Res. 1, 10 doi: 10.1186/s42483-019-0016-8

    Adnan M, Hamada MS, Hahn M, Li G-Q, Luo C-X (2019) Fungicide resistance of Botrytis cinerea from strawberry to procymidone and zoxamide in Hubei, China. Phytopathol. Res. 1, 17 doi: 10.1186/s42483-019-0024-8

    Weber RWS, Hahn M (2019) Grey mould disease of strawberry in northern Germany: causal agents, fungicide resistance and management strategies. Appl. Microbiol. Biotechnol. 103, 1589-1597 doi: 10.1007/s00253-018-09590-1

    2018

    Yin Y, Wu S, Chui C, Ma T, Jiang H, Hahn M, Ma Z (2018) The MAPK kinase BcMkk1 suppresses oxalic acid biosynthesis via impeding phosphorylation of BcRim15 by BcSch9 in Botrytis cinerea. PLoS Pathog. 2018 Sep 13;14(9):e1007285. doi: 10.1371/journal.ppat.1007285. eCollection 2018 Sep.

    Müller N, Leroch M, Schumacher J, Zimmer D, Könnel A, Klug K, Leisen T, Scheuring D, Sommer F, Mühlhaus T, Schroda M, Hahn M (2018) Investigations on VELVET regulatory mutants confirm the role of host tissue acidification and secretion of proteins in the pathogenesis of Botrytis cinerea. New Phytol. 219, 1062-1074.
    doi: 10.1111/nph.15221

    2017

    Rupp S, Plesken C, Rumsey S, Dowling M, Schnabel G, Weber RWS, Hahn M (2017) Botrytis fragariae, a new species causing gray mold on strawberries, shows high frequencies 1 of specific and efflux-based fungicide resistance. Appl. Environ. Microbiol. 83:e00269-17 doi:10.1128/AEM.00269-17
    Supplemental Material

    van Kan JAL, Stassen JHM, Mosbach A, van der Lee TAJ, Faino L, Farmer AD, Papasotiriou D, Zhou S, Seidl MF, Cottam E, Edel D, Hahn M, Schwartz DC, Dietrich RA, Widdison S, Scalliet G (2017) A gapless genome sequence of the fungus Botrytis cinerea. Mol. Plant Pathol. 18, 75-89 doi: 10.1111/mpp.12384

    Rupp S, Weber RW, Rieger D, Detzel P, Hahn M (2017) Spread of Botrytis cinerea strains with multiple fungicide resistance in German horticulture. Frontiers in Microbiology 7, 2017, 2075 doi: 10.3389/fmicb.2016.02075
    Supplemental Material

    2016

    Daumann M, Golfier P, Knüppel N, Hahn M, Möhlmann T (2016) Botrytis cinerea can import and utilize nucleosides in salvage and catabolism and BcENT functions as high affinity nucleoside transporter. Fungal Biology 120, 904-916 doi: 10.1016/j.funbio.2016.05.012
    Supplementary data

    2015

    Plesken C, Weber, RWS, Rupp S, Leroch M, Hahn M (2015) Botrytis pseudocinerea is a significant pathogen of several crop plants but susceptible to displacement by fungicide-resistant B. cinerea strains. Appl. Environ. Microbiol. 81, 7048-7056 doi: 10.1128/AEM.01719-15
    Supplemental material

    Konstantinou S, Veloukas T, Leroch M, Menexes G, Hahn M, Karaoglanidis G (2015) Population structure, fungicide resistance profile, and sdhB mutation frequency of Botrytis cinerea from strawberry and greenhouse-grown tomato in Greece. Plant Dis. 99, 240-248 doi: 10.1094/PDIS-04-14-0373-RE

    Hahn M, Leroch M (2015) Multidrug efflux transporters. In: Fungicide Resistance in Plant Pathogens: Principles and a Guide to Practical Management (Ishii H, Hollomon D., eds.), 2015, Springer Japan KK, Tokyo. pp 233-250 doi: 10.1007/978-4-431-55642-8_15

    Leroch M, Mueller N, Hinsenkamp I, Hahn M (2015) The signaling mucin Msb2 regulates surface sensing and host penetration via BMP1-MAP kinase signaling in Botrytis cinerea. Mol. Plant Pathol. 16, 797-798 doi: 10.1111/mpp.12234

    Plesken C, Westrich L-D, Hahn M (2015) Genetic and phenotypic characterization of Botrytis calthae. Plant Pathol. 64, 128–136 doi: 10.1111/ppa.12240

    2014

    Hyde et al. (2014) One stop shop: backbones trees for important phytopathogenic genera I. Fungal Diversity 67, 21-125 doi: 10.1007/s13225-014-0298-1

    Hahn M, Viaud M, van Kan J (2014) The genome of Botrytis cinera, a ubiquitous broad host range necrotroph. In: Genomics of Plant-Associated Fungi and Oomycetes: Dicot Pathogens, Dean RA et al. (eds.), Springer-Verlag Berlin Heidelberg 2014. pp 19-44 doi: 10.1007/978-3-662-44056-8_2

    Hahn M (2014) The rising threat of fungicide resistance in plant pathogenic fungi: Botrytis as a case study. J. Chem. Biol. 28, 133-141 doi: 10.1007/s12154-014-0113-1

    2013

    Hahn M, Plesken C, Leroch M, Düker A, Rupp S, Weber R (2013) Multiple fungicide resistance and genetic diversity of Botrytis spp. in German strawberry fields. In: Dehne, HW, Deising HB, Fraaije B, Gisi U, Hermann D, Mehl A, Oerke EC, Russell PE, Stammler G, Kuck KH and Lyr H (Eds) "Modern Fungicides and Antifungal Compounds", Vol. VII,, pp. 129-134. Deutsche Phytomedizinische Gesellschaft, Braunschweig, ISBN: 978 3 941261 13 6

    Czepukojc B, Leroch M, Salm F, Viswanathan UM, Burkholz T, Hahn M, Jacob C (2013) Antifungal activity of Tetrasulfanes against Botrytis cinerea. Nat. Prod. Comm. 8, 1599-1603 PMID: 24427951

    Yang Q, Jiang J, Mayr C, Hahn M, Ma Z (2013) Involvement of two type 2C protein phosphatases BcPtc1 and BcPtc3 in the regulation of multiple stress tolerance and virulence of Botrytis cinerea. Environm. Microb. 15, 2696–2711 doi: 10.1111/1462-2920.12126

    Leroch M, Kleber A, Silva E, Coenen T, Koppenhöfer D, Shmaryahu A, Valenzuela PDT, Hahn M (2013) Transcriptome profiling of Botrytis cinerea conidial germination reveals upregulation of infection-related genes during the prepenetration stage. Eukaryotic Cell 12:614-626 doi: 10.1128/EC.00295-12
    Supplements

    Leroch M, Plesken C, Weber RWS, Kauff F, Scalliet G, Hahn M (2013) Gray mold populations in German strawberry fields are resistant to multiple fungicides and dominated by a novel clade closely related to Botrytis cinerea. Appl. Environm. Microbiol. 79, 159-167 doi: 10.1128/AEM.02655-12
    Supplements

    2011

    Mernke D, Dahm S, Walker A-S, Lalève A, Fillinger S, Leroch M, Hahn M (2011) Two promoter rearrangements in a drug efflux transporter gene are responsible for the appearance and spread of multidrug resistance phenotype MDR2 in B. cinerea isolates in French and German vineyards. Phytopathology 101, 1176-1183

    Samuel S, Papayiannis LC, Leroch L, Veloukas T, Hahn M, Karaoglanidis GS (2011) Evaluation of the incidence of the G143A mutation and cytb intron presence in the cytochrome bc-1 gene conferring QoI resistance in Botrytis cinerea populations from several hosts. Pest Manag. Sci. 67 1029-1036

    Veloukas T, Leroch M Hahn M, Karaoglanidis GS (2011) Detection and molecular characterization of boscalid-resistant Botrytis cinerea isolates from strawberry. Plant Disease 95, 1302-1307

    Leroch M, Kretschmer M, Hahn M (2011) Fungicide resistance phenotypes of Botrytis cinerea isolates from commercial vineyards in South West Germany, J. Phytopathol. 159, 63–65

    Amselem J et al. (2011) Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLoS Genet. 2011 August; 7(8): e1002230.

    Leroch M, Mernke D, Koppenhoefer D, Schneider P, Mosbach A, Doehlemann G, Hahn M (2011) Living colors in the gray mold pathogen Botrytis cinerea: Codon-optimized genes encoding green fluorescent protein and mCherry, which exhibit bright fluorescence. Appl Environ Microbiol 77:2877-2897. Weber RWS, Hahn M. 2011. A rapid and simple method for determining fungicide resistance in Botrytis. J. Plant Dis. Prot. 108, 662-671

    Mosbach A, Leroch M, Mendgen KW, Hahn M (2011) Lack of evidence for a role of hydrophobins in conferring surface hydrophobicity to conidia and hyphae of Botrytis cinerea. BMC Microbiol. 11, 10

    2010

    Leroux P, Gredt M, Leroch M, Walker A-S (2010) Exploring mechanisms of resistance to respiratory inhibitors in field strains of Botrytis cinerea, the causal agent of gray mold. Applied Env Microbiol 76, 6615-6630

    Schamber A, Leroch M, Diwo J, Mendgen K, Hahn M (2010) The role of mitogen-activated protein (MAP) kinase signalling components and the Ste12 transcription factor in germination and pathogenicity of Botrytis cinerea. Mol. Plant Pathol. 11, 105-119

    2009

    Kretschmer M, Leroch M, Mosbach A, Walker A-S, Fillinger S, Mernke D, Schoonbeek H-J, Pradier J-M, Leroux P, De Waard MA, Hahn M (2009) Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea. PLoS Pathog 5(12): e1000696

    Stefanato F, Abou-Mansour E, Buchala A, Kretschmer M, Mosbach A, Hahn M, Bochet C, Metraux J-P, Schoonbeek H-J (2009) The ABC-transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana. Plant J. 58, 499-510

    2008

    Kucheryava N, Bowen JK, Sutherland PW, Conolly JJ, Mesarich CH, Rikkerink EH, Kemen E, Plummer KM, Hahn M, Templeton MD (2008) Two novel Venturia inaequalis genes induced upon morphogenetic differentiation during infection and in vitro growth on cellophane. Fungal Genet. Biol. 45, 1329-1339

    Kretschmer M, Hahn M. 2008. Fungicide resistance and genetic diversity of Botrytis cinerea isolates from a vineyard in Germany. J. Plant Dis. Prot. 115, 214-219

    Voegele RT, Hahn M, Mendgen K. 2008. Uredinales: Cytology, Biochemistry, and Molecular Biology. In: Plant Relationships, 2nd Edition (The Mycota V). H. Deising (Ed.) Springer Verlag Berlin Heidelberg, p. 69-98.

    2007

    Kretschmer M, Kassemeyer HH, Hahn M (2007) Age-dependent grey mould susceptibility and tissue-specific defence gene activation of grapevine berry skins after infection by Botrytis cinerea. J. Phytopathology 155, 258-263

    Rui O, Hahn M (2007) The Botrytis cinerea hexokinase, Hxk1, but not the glucokinase, Glk1, is required for normal growth and sugar metabolism, and for pathogenicity on fruits. Microbiology, 153, 2791-2802

    Rui O, Hahn M (2007) The Slt2-type MAP kinase Bmp3 of Botrytis cinerea is required for normal saprotrophic growth, conidiation, plant surface sensing and host tissue colonization. Mol. Plant Pathol. 8, 173-184

    2006

    Doehlemann, G, Berndt P, Hahn M (2006) Trehalose metabolism is important for heat stress tolerance and spore germination of Botrytis cinerea. Microbiology 152, 2625-2634

    Doehlemann G, Berndt P, Hahn M (2006) Different signalling pathways involving a Ga protein, cAMP and a MAP kinase control germination of Botrytis cinerea conidia. Mol. Microbiol. 59, 821-835

    2005

    Jakupovic M, Heintz M, Reichmann P, Mendgen K, Hahn M (2005) Microarray analysis of expressed sequence tags from haustoria of the rust fungus Uromyces fabae. Fungal Genetics and Biology 43, 8-19

    Link T, Lohaus G, Heiser I, Mendgen K, Hahn M, Voegele RT (2005) Characterization of a novel NADP+-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae. Biochem. J. 389, 289-295

    Kemen E, Kemen AC, Rafiqi M, Hempel U, Mendgen K, Hahn M, Voegele RT (2005)  Identification of a protein from rust fungi that is transferred from haustoria into the plant host cell. Mol. Plant-Microbe Interact. 18, 1130-1139

    Doehlemann G, Molitor F, Hahn M (2005) Molecular and functional characterization of a fructose specific transporter from the gray mold fungus Botrytis cinerea. Fungal Genetics and Biology 42, 601-610

    Reis H, Pfiffi S, Hahn M (2005) Molecular and functional characterization of a secreted lipase from Botrytis cinerea. Mol. Plant Pathol. 6, 257-267

    Kemen E, Hahn M, Mendgen K, Struck C (2005) Different resistance mechanisms of Medicago truncatula ecotypes against the rust fungus Uromyces striatus. Phytopathology 95, 153-157

    2004

    Voegele RT, Hahn M, Lohaus G, Link T, Heiser I, Mendgen K (2004) Possible roles for mannitol and mannitol dehydrogenase in the biotrophic plant pathogen Uromyces fabae. Plant Physiol. 137, 190-198

    Hahn M (2004) Mechanisms of Infection: Rusts. In: Encyclopedia of Plant and Crop Science. Marcel Dekker, New York; pp. 701-704

    Weber RWS, Stenger E, Meffert A, Hahn M (2004) Brefeldin A production by Phoma medicaginis in dead pre-colonized plant tissue: a strategy for habitat conquest? Mycol. Res. 108, 662-671

    2002

    Struck S, Ernst M, Hahn M (2002) Characterization of a developmentally regulated amino acid transporter (AAT1p) of the rust fungus Uromyces fabae. Mol. Plant Pathol. 3, 23-30 doi:

    Mendgen K, Hahn M (2002) Plant infection and the establishment of fungal biotrophy. TIPS 7, 352-356

    2001

    Hahn M, Mendgen K (2001) Signal and nutrient exchange at biotrophic plant-fungus interfaces. Curr. Opin. Plant Biol. 4, 322-327 doi: 10.1016/S1369-5266(00)00180-1

    Voegele RT, Struck C, Hahn M, Mendgen K (2001) The role of haustoria in sugar supply during infection of broad bean by the rust fungus Uromyces fabae. PNAS 98, 8133-8138 doi: 10.1073/pnas.131186798

    2000

    Sohn J, Voegele RT, Mendgen K, Hahn M (2000) High level activation of vitamin B1 biosynthesis genes in haustoria of the rust fungus Uromyces fabae. Mol. Plant-Microbe Interact. 13, 629-636 doi: 10.1094/MPMI.2000.13.6.629

    Mendgen K, Struck C, Voegele RT, Hahn M (2000) Biotrophy and rust haustoria. Physiol. Mol. Plant Pathol. 56, 141-145 doi: 10.1006/pmpp.2000.0264

    Hahn M (2000) The Rust Fungi. Cytology, Physiology and Molecular Biology of Infection. In: Fungal Pathology (ed. JW Kronstad) pp. 267-306, Dordrecht: Kluwer Academic Publishers link

    1998

    Struck C, Hahn M, Mendgen K (1998) Infection structures of plant pathogenic fungi - potential targets for plant disease control. J. Plant Dis. Prot. 105, 581-589 link

    Struck C, Siebels C, Rommel O, Wernitz M, Hahn M (1998) The plasma membrane H+-ATPase from the biotrophic rust fungus Uromyces fabae: Molecular characterization of the gene (PMA1) and functional expression of the enzyme in yeast. Mol. Plant-Microbe Interact. 11, 458-465 doi: 10.1094/MPMI.1998.11.6.458

    1997

    Hahn M, Mendgen K (1997) Characterization of in planta-induced rust genes isolated from a haustorium-specific cDNA library. Mol. Plant-Microbe Interact. 10, 427-437 doi: 10.1094/MPMI.1997.10.4.427

    Hahn M, Neef U, Struck C, Goettfert M, Mendgen K (1997) A putative amino-acid transporter is specifically expressed in haustoria of the rust fungus Uromyces fabae. Mol. Plant-Microbe Interact. 10, 438-445 doi: 10.1094/MPMI.1997.10.4.438

    Leibinger W, Breuker B, Hahn M, Mendgen K (1997) Control of postharvest pathogens and colonization of the apple surface by antagonistic microorganisms in the field. Phytopathology 87, 1103-1110 doi: 10.1094/PHYTO.1997.87.11.1103

    Hahn M, Deising H, Struck C, Mendgen K (1997) Mechanisms by which pathogenic fungi recognize and attack their host plants. In: Resistance of Crop Plants against Fungi (H. Hartleb, R. Heitefuss and H.-H. Hoppe, eds.), 33-57. Fischer Verlag, Jena link

    1996

    Struck C, Hahn M, Mendgen K (1996) The plasma membrane H+-ATPase activity in spores, germ tubes, and haustoria of the rust fungus Uromyces viciae-fabae. Fungal. Genet. Biol. 20, 30-35 doi: 10.1006/fgbi.1996.0006

    Mendgen K, Hahn M, Deising H (1996) Morphogenesis and mechanisms of penetration by plant pathogenic fungi. Annu. Rev. Phytopathol. 34, 367-386 doi: 10.1146/ANNUREV.PHYTO.34.1.367

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