Fachgebiet Zellbiologie



  • Beck-Sickinger A, Schwappach-Pignataro B, Herrmann JM, Buchner J. 2019. Open Access und die Zukunft wissenschaftlicher Veröffentlichungen. BioSpektrum 05/2019, 25, 245.
  • Bekeova C, Anderson-Pullinger L, Boye K, Boos F, Sharpadskaya Y, Herrmann JM, Seifert EL. 2019. Multiple mitochondrial thioesterases have distinct tissue and substrate specificity, and CoA regulation, suggesting unique functional roles. J Biol Chem. 294, 19034-19047.
  • Saladi S, Boos F, Poglitsch M, Meyer H, Sommer F, Mühlhaus S, Schroda M, Schuldiner M, Madeo F, Herrmann JM. 2019. The NADH Dehydrogenase Nde1 Executes Cell Death after Integrating Signals from Metabolism and Proteostasis on the Mitochondrial Surface. Molecular Cell 77, 1–14.
  • Odendall F, Backes S, Tatsuta T, Weill U, Schuldiner M, Langer T, Herrmann JM, Rapaport D, Dimmer KS. 2019. The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism. Mol Biol Cell. 30, 2681-2694.
  • Laborenz J, Hansen KG, Prescianotto-Baschong C, Spang A, Herrmann JM. 2019. In vitro import experiments with semi-intact cells suggest a role of the Sec61 paralog Ssh1 in mitochondrial biogenesis. Biol Chem. 400, 1229-1240.
  • Lill R, Langer T, Herrmann JM. 2019. Walter Neupert (1939-2019), a pioneer of mitochondrial biogenesis and morphology. EMBO J. 38, e103100.
  • Hansen KG, Herrmann JM. 2019. Transport of Proteins into Mitochondria. Protein J. 38, 330-342.
  • Boos F, Krämer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zöller E, van der Laan M, Savitski MM, Benes V, Herrmann JM. 2019. Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme. Nat Cell Biol. 21, 442-451.
  • Backes S, Garg SG, Becker L, Peleh V, Glockshuber R, Gould SB, Herrmann JM. 2019. Development of the mitochondrial intermembrane space disulfide relay represents a critical step in eukaryotic evolution. Mol Biol Evol. 36, 742-756.
  • Antunes D, Chowdhury A, Aich A, Saladi S, Harpaz N, Stahl M, Schuldiner M, Herrmann JM, Rehling P, Rapaport D. 2019. Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1. J Mol Med 97, 269-279.


  • Herrmann JM, Carvalho P, Hayer-Hartl M, Yoshihisa T. 2018. Life of proteins: from nascent chain to degradation. Nat Struct Mol Biol. 25, 996-999.
  • Herrmann JM. 2018. A force-generating machine in the plant's power house: a pulling AAA ATPase motor drives protein translocation into chloroplasts. The Plant Cell 30, 2646–2647.
  • Hansen KG, Aviram N, Laborenz J, Bibi C, Meyer M, Spang A, Schuldiner M, Herrmann JM. 2018. An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast. Science 361, 1118-1122.
  • Weill U, Yofe I, Sass E, Stynen B, Davidi D, Natarajan J, Ben-Menachem R, Avihou Z, Goldman O, Harpaz N, Chuartzman S, Kniazev K, Knoblach B, Laborenz J, Boos F, Kowarzyk J, Ben-Dor S, Zalckvar E, Herrmann JM, Rachubinski RA, Pines O, Rapaport D, Michnick SW, Levy ED, Schuldiner M. 2018. Genome-wide SWAp-Tag yeast libraries for proteome exploration. Nat Methods 15, 617-622.
  • Zöller E, Todd Alexander R, Herrmann JM. 2018. Proteasomal degradation competes with Mia40-mediated import into mitochondria. BMC Biol. 2018. 16, 63.
  • Backes S, Hess S, Boos F, Woellhaf MW, Gödel S, Jung M, Mühlhaus T, Herrmann JM. 2018. Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences. J Cell Biol. 217, 1369-82.
  • Hansen KG, Boos F, Herrmann JM. 2018. Accessory signals in protein translocation. Aging, 10, 530-531.
  • Boos F, Mühlhaus T, Herrmann JM. 2018. Detection of Internal Matrix Targeting Signal-like Sequences (iMTS-Ls) in Mitochondrial Precursor Proteins Using the TargetP Prediction Tool. Bio-protocol Vol 8, Issue 17, Sep 05.
  • Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F. 2018. Guidelines and recommendations on yeast cell death nomenclature. Microb Cell 5, 4-31. 


  • Backes S, Herrmann JM. 2017. Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces. Front Mol Biosci. 4, 83.
  • Peleh, V, Zannini F, Backes S, Rouhier N, Herrmann JM. 2017. Erv1 of Arabidopsis thaliana can directly oxidize mitochondrial intermembrane space proteins in the absence of redox-active Mia40. BMC Biology, 15:106
  • Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D. 2017. Coi1 is a novel assembly factor of the yeast complex III-complex IV  supercomplex. Mol. Biol. Cell mbc.E17-05-0317
  • Ure ME, Heydari E, Pan W, Ramesh A, Rehman S, Morgan C, Pinsk M, Erickson R, Herrmann JM, Dimke H, Cordat E, Lemaire M, Walter M, Alexander RT. 2017. A variant in a cis-regulatory element enhances claudin-14 expression and is associated with pediatric-onset hypercalciuria and kidney stones. Hum Mutat. 2017 Jun;38(6):649-657
  • Ullrich P, Herrmann JM. 2017. Q&A with Johannes Herrmann, new President of German Society for Biochemistry and Molecular Biology (GBM). Elsevier Content.


  • Peleh V, Cordat, E, Herrmann JM. 2016. Mia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding. eLIFE 25;5. pii: e16177
  • Alfaiz AA, Müller V, Boutry-Kryza N, Ville D, Guex N, de Bellescize J, Rivier C, Labalme A, des Portes V, Edery P, Till M, Xenarios I, Sanlaville D, Herrmann JM, Lesca G, Reymond A. 2016. West syndrome caused by homozygous variant in the evolutionary conserved gene encoding the mitochondrial elongation factor GUF1. Eur J Hum Genet. 24, 1001-8
  • Hansen KG, Schlagowski A, Herrmann JM. 2016. Escorted by chaperones: Sti1 helps to usher precursor proteins from the ribosome to mitochondria. FEBS J. 283, 3335-7
  • Woellhaf MW, Sommer F, Schroda M, Herrmann JM. 2016. Proteomic profiling of the mitochondrial ribosome identifies Atp25 as a composite mitochondrial precursor protein. Mol Biol Cell. 27, 3031-3039
  • Ramesh A, Peleh V, Martinez-Caballero S, Wollweber F, Sommer F, van der Laan M, Schroda M, Alexander RT, Campo ML, Herrmann JM. 2016. A disulfide bond in the TIM23 complex is crucial for voltage gating and mitochondrial protein import. J Cell Biol. 214, 417-31
  • Boos F, Wollin M, Herrmann JM. 2016 Methionine on the rise: how mitochondria changed their codon usage. EMBO J. 35, 2066-2067


  • Beckmann R, Herrmann JM. 2015. Mitoribosome oddities. Science 348:288-289
  • Bode M, Woellhaf MW, Bohnert M, van der Laan M, Sommer F, Jung M, Zimmermann R, Schroda M, Herrmann JM. 2015. Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase. Mol Biol Cell 26, 2385-401
  • van der Sluis EO, Bauerschmitt H, Becker T, Mielke T, Frauenfeld J, Berninghausen O, Neupert W, Herrmann JM, Beckmann R. 2015. Parallel structural evolution of mitochondrial ribosomes and OXPHOS complexes. Genome Biol Evol. 7, 1235-51
  • Pfeffer S, Woellhaf MW, Herrmann JM, Förster F. 2015. Organization of the mitochondrial translation machinery studied in situ by cryoelecton tomography. Nat Commun. 6, 6019
  • Riemer J, Schwarzländer M, Conrad M, Herrmann JM. 2015. Thiol switches in mitochondria: operation and physiological relevance. Biol Chem 396, 465-482
  • Herrmann JM, Becker K, Dick TP. 2015. Highlight: The Many Faces of Thiol Switches. Biol Chem. 396, 385-387
  • Peleh V, Ramesh A, Herrmann JM. 2015. Import of proteins into isolated yeast mitochondria. Methods Mol Biol. 1270, 37-50
  • Herrmann JM, Spang A. 2015. Intracellular parcel service: current issues in intracellular trafficking. Methods Mol Biol. 1270, 1-12
  • Kojer K, Peleh V, Calabrese G, Herrmann JM, Riemer J. 2015. Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial IMS. Mol Biol Cell. 26, 195-204


  • Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EMA, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A. 2014. MPV17L2 is required for ribosome assembly in mitochondria. Nucleic Acids Research 42, 8500-8515
  • Woellhaf MW, Hansen KG, Garth C, Herrmann JM. 2014. Import of ribosomal proteins into yeast mitochondria. Biochemistry and Cell Biology 92, 489-498
  • Herrmann JM, Riemer J. 2014. Three approaches to one problem: Protein folding in the periplasm, the endoplasmic reticulum and the intermembrane space. Antioxid Redox Signal. 21, 438-456
  • Peleh V, Riemer J, Dancis A, Herrmann JM. 2014. Protein oxidation in the intermembrane space of mitochondria is substrate-specific rather than general. Microbial Cell 1, 81-93
  • Longen S, Woellhaf MW, Petrungaro C, Riemer J, Herrmann JM. 2014. The Disulfide Relay of the Intermembrane Space Oxidizes the Ribosomal Subunit Mrp10 on Its Transit into the Mitochondrial Matrix. Developmental Cell 28, 30-42


  • Herrmann JM. 2013. The bacterial membrane insertase YidC is a functional monomer and binds ribosomes in a nascent chain-dependent manner.. J Mol Biol. 425, 4071-4073
  • Weckbecker D, Herrmann JM. 2013. Methods to study the biogenesis of membrane proteins in yeast mitochondria. Methods Mol Biol. 1033, 307-322
  • Hoffmann C, Plocharski B, Haferkamp I, Leroch M, Ewald R, Bauwe H, Riemer J, Herrmann JM, Neuhaus HE. 2013.From endoplasmic reticulum to mitochondria: absence of the Arabidopsis ATP antiporter endoplasmic Reticulum Adenylate Transporter1 perturbs photorespiration.. Plant Cell. 25, 2647-2660
  • Bode M, Longen S, Morgan B, Peleh V, Dick TP, Bihlmaier K, Herrmann JM. 2013. Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest. Antioxid Redox Signal. 18, 1597-1612
  • Fischer M, Horn S, Belkacemi A, Kojer K, Petrungaro C, Habich M, Ali M, Kuttner V, Bien M, Kauff F, Dengjel J, Herrmann JM, Riemer J. 2013. Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. Mol Biol Cell. 24, 2160-2170
  • Herrmann JM, Neupert W. 2013. Protein import into Mitochondria (Chapter). The Encyclopedia of Biological Chemistry 2nd edition, vol. 3, 632-636, Waltham, MA: Adademic Press
  • Herrmann JM. 2013. Oxidative Proteinfaltung: Der mitochondriale Intermembranraum ist voller Überraschungen. BIOspektrum 19, 247-249
  • Funes S, Westerburg H, Jaimes-Miranda F, Woellhaf MW, Luis Aguilar-López J, Janßen L, Bonnefoy N, Kauff F, Herrmann JM. 2013. Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle reveals insights into the evolution of the co-translational insertion systems. FEBS J. 280, 904-915
  • Herrmann JM, Woellhaf MW, Bonnefoy N. 2013. Control of protein synthesis in yeast mitochondria: the concept of translational activators. Biochim Biophys Acta 1822, 286-294


  • Weckbecker D, Longen S, Riemer J, Herrmann JM. 2012. Atp23 biogenesis reveals a chaperone-like folding activity of Mia40 in the IMS of mitochondria. EMBO J. 31, 4348-4358
  • Keil M, Bareth B, Woellhaf MW, Peleh V, Prestele M, Rehling P, Herrmann JM. 2012. Oxa1-ribosome complexes coordinate the assembly of cytochrome c oxidase in mitochondria. J Biol Chem. 287, 34484-34493
  • Hildenbeutel M, Theis M, Geier M, Haferkamp I, Neuhaus HE, Herrmann JM, Ott M. 2012. The membrane insertase Oxa1 is required for efficient import of carrier proteins into mitochondria. J Mol Biol. 423, 590-599
  • Herrmann JM, Longen S, Weckbecker D, Depuydt M. 2012. Biogenesis of mitochondrial proteins. Adv Exp Med Biol. 748, 41-64
  • Krueger V, Deckers M, Hildenbeutel M, Van der Laan M, Hellmers M, Drekers C, Preuss M, Herrmann JM, Rehling P, Wagner R, Meinecke M. 2012. The mitochondrial oxidase-assembly-protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers. J Biol Chem. 287, 33314-33326
  • Herrmann JM, Dick TP. 2012. Redox Biology on the Rise. Biol Chem. 393, 999-1004


  • Herrmann JM. 2011. MINOS is plus: a Mitofilin complex for mitochondrial membrane contacts. Dev Cell. 21, 599-600
  • Gruschke S, Kehrein K, Römpler K, Gröne K, Israel L, Imhof A, Herrmann JM, Ott M. 2011. Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol. 193, 1101-1114
  • Riemer J, Fischer M, Herrmann JM. 2011. Oxidation-driven protein import into mitochondria: Insights and blind spots. Biochim Biophys Acta. 1808, 981-989
  • Funes S, Kauff F, van der Sluis EO, Ott M, Herrmann JM. 2011. Evolution of YidC/Oxa1/Alb3 insertases: three independent gene duplications followed by functional specialization in bacteria, mitochondria and chloroplasts. Biol Chem. 392, 13-19
  • Riemer J, Herrmann JM. 2011. Protein import into the intermembrane space of mitochondria. Methods in Protein Chemistry, Chapter 6, 95-112.


  • Klöppel C, Michels C, Zimmer J, Herrmann JM, Riemer J. 2010. In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress. Biochem Biophys Res Commun. 403, 114-119
  • Herrmann JM. 2010. Ups delivery to the intermembrane space of mitochondria: a novel affinity-driven protein import pathway. EMBO J. 29, 2859-2860
  • Bohnert M, Rehling P, Guiard B, Herrmann JM, Pfanner N, van der Laan M. 2010. Cooperation of stop-transfer and conservative sorting mechanisms in mitochondrial protein transport. Curr Biol. 20, 1227-1232
  • Herrmann JM, Riemer J. 2010. Oxidation and reduction of cysteines in the intermembrane space of mitochondria: Multiple facets of redox-control. Antioxid Redox Signal. 13, 1323-1326
  • Bauerschmitt H, Mick DU, Deckers M, Vollmer C, Funes S, Kehrein K, Ott M, Rehling P, Herrmann JM. 2010. Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell 21, 1937-1944
  • Gruschke S, Groene K, Heublein M, Hölz S, Israel L, Imhof A, Herrmann JM, Ott M. 2010. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem. 285, 19022-19028
  • Herrmann JM, Riemer J. 2010. The intermembrane space of mitochondria. Antioxid Redox Signal. 13, 1341-1358
  • Bien M, Longen S, Wagener N, Chwalla I, Herrmann JM, Riemer J. 2010. Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione. Mol Cell 37, 516-528
  • Herrmann JM, Bien M, Riemer J. 2010. Die Mechanik der oxidativen Proteinfaltung in Mitochondrien. GIT Laborfachzeitschrift 54, 470-472
  • Ott M, Herrmann JM. 2010. Co-translational insertion of mitochondrially encoded proteins. Biochim Biophys Acta 1803, 767-775
  • Ilkow CS, Weckbecker D, Cho WJ, Meier S, Beatch MD, Goping IS, Herrmann JM, Hobman TC. 2010. The rubella virus capsid protein inhibits mitochondrial import. J Virol. 84, 119-130


  • Longen S, Bien M, Bihlmaier K, Kloeppel C, Kauff F, Hammermeister M, Westermann B, Herrmann JM, Riemer J. 2009 Systematic Analysis of the Twin Cx(9)C Protein Family. J Mol Biol. 393, 356-368
  • Riemer J, Bulleid N, Herrmann JM. 2009. Disulfide formation in the ER and mitochondria: two solutions to a common process. Science 324, 1284-1287
  • Prestele M, Vogel F, Reichert AS, Herrmann JM, Ott M. 2009. Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation. Mol Biol Cell 20, 2615-2625
  • Herrmann JM. 2009. Putting a break on protein translocation: metabolic regulation of mitochondrial protein import. Mol Microbiol. 72, 275-278
  • Funes S, Hasona A, Bauerschmitt H, Grubbauer C, Kauff F, Collins R, Crowley PJ, Palmer SR, Brady LJ, Herrmann JM. 2009. Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function. Proc Natl Acad Sci USA. 106, 6656-6661
  • Eckers E, Bien M, Stroobant V, Herrmann JM, Deponte M. 2009. Biochemical Characterization of Dithiol Glutaredoxin 8 from Saccharomyces cerevisiae: The Catalytic Redox Mechanism Redux (dagger). Biochemistry 48, 1410-1413
  • Herrmann JM, Kauff F and Neuhaus HE. 2009. Thiol oxidation in bacteria, mitochondria and chloroplasts: Common principles but three unrelated machineries? Biochim Biophys Acta. 1793, 71-77



  • Bihlmaier K, Mesecke N, Terziyska N, Bien M, Hell K and Herrmann JM. 2007. The disulfide relay system of mitochondria is connected to the respiratory chain. J Cell Biol. 179, 389-395
  • van Bloois E, Koningstein G, Bauerschmitt H, Herrmann JM and Luirink J. 2007. Saccharomyces cerevisiae Cox18 complements the essential Sec-independent function of Escherichia coli YidC. FEBS J. 274, 5704-5713
  • Funes S, Herrmann JM. 2007. Analysis of mitochondrial protein synthesis in yeast. In: Methods in Molecular Biology. Mitochondria, Practical Protocols, Volume 372, eds. Leister D, Herrmann JM. Methods Mol Biol. 372, 255-263
  • Leister D, Herrmann JM (editors). 2007. Methods in Molecular Biology. Mitochondria, Practical Protocols Methods Mol Biol. 372
  • Herrmann JM, Bihlmaier K, Mesecke N. 2007. The Role of the Mia40-Erv1 Disulfide Relay System in Import and Folding of Proteins of the Intermembrane Space of Mitochondria. In: The Enzymes: Molecular Machines Involved in Protein Transport across Cellular Membranes 25, eds. Koehler C, Dalbey R. Academic Press, 345-366
  • Herrmann JM and Köhl R. 2007. Catch me if you can! Oxidative protein trapping in the intermembrane space of mitochondria. J Cell Biol. 176, 559-563
  • Herrmann JM and Westermann B. 2007. Analysis of protein-protein interactions in mitochondria. Methods in Cell Biology 80, 743-759
  • Martinez-Caballero S, Grigoriev SM, Herrmann JM, Campo ML and Kinnally KW. 2007. Tim17p regulates the twin-pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem. 282, 3584-3593
  • Terziyska N, Grumbt B, Bien M, Neupert W, Herrmann JM and Hell K. 2007. The sulfhydryl oxidase Erv1 is a substrate of the Mia40-dependent protein translocation pathway. FEBS Lett. 581, 1098-1102
  • Neupert W and Herrmann JM. 2007. Translocation of Proteins into Mitochondria. Annu Rev Biochem. 76, 723-749 


  • Khalimonchuk O, Ott M, Funes S, Ostermann K, Rödel G and Herrmann JM. 2006. Sequential processing of a mitochondrial tandem protein: Insights into the protein import in Schizosaccharomyces pombe. Eukaryotic Cell 5, 997-1006
  • Ott M, Prestele M, Bauerschmitt H, Funes S, Bonnefoy N and Herrmann JM. 2006. Mba1, a membrane-associated ribosome receptor in mitochondria. EMBO J. 25, 1603-1610 


  • Meier S, Neupert W and Herrmann JM. 2005. Proline residues of transmembrane domains determine the sorting of inner membrane proteins in mitochondria. J Cell Biol. 170, 881-888
  • Mesecke N, Terziyska N, Kozany C, Baumann F, Neupert W, Hell K and Herrmann JM. 2005. A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121, 1059-1069
  • Herrmann JM and Hell K. 2005. Chopped, trapped or tacked - Protein translocation into the intermembrane space of mitochondria. Trends in Biochemical Science 30, 205-212
  • Herrmann JM. 2005. Proteintransportmaschinen in Mitochondrien - Ein Mosaik aus Proteinkomplexen unterschiedlicher phylogenetischer Abstammung. Naturwissenschaftliche Rundschau 10, 525-530
  • Stadler SC, Polanetz R, Meier S, Mayerhofer PU, Herrmann JM, Anslinger K, Roscher AA, Röschinger W and Holzinger A. 2005. Mitochondrial targeting signals and mature peptides of 3-methylcrotonyl-CoA carboxylase. BBRC 334, 939-946
  • Bloois EV, Nagamori S, Koningstein G, Ullers RS, Preuss M, Oudega B, Harms N, Kaback HR, Herrmann JM and Luirink J. 2005. The Sec-independent function of E. coli YidC is evolutionary conserved and essential. J Biol Chem. 280, 12996-13003
  • Preuss M, Ott M, Funes S, Luirink J and Herrmann JM. 2005. Evolution of mitochondrial Oxa proteins from bacterial YidC: Inherited and acquired functions of a conserved protein insertion machinery. J Biol Chem. 280, 13004-13011
  • Herrmann JM and Funes S. 2005. Biogenesis of cytochrome oxidase - sophisticated assembly lines in the mitochondrial inner membrane. Gene 354, 43-52
  • Meier S, Neupert W and Herrmann JM. 2005. Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J Biol Chem. 280, 7777-7785
  • Terziyska N, Lutz T, Kozany C, Mokranjac D, Mesecke N, Neupert W, Herrmann JM and Hell K. 2005. Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett. 579, 179-184


  • Herrmann JM and Neupert W. 2004. Protein import into mitochondria. Encyclopedia of Biological Chemistry 3, 510-515
  • Funes S, Gerdes L, Inaba M, Soll J and Herrmann JM. 2004. The Arabidopsis thaliana chloroplast inner envelope protein ARTEMIS is a functional member of the Alb3/Oxa1/YidC family of proteins. FEBS Lett. 569, 89-93
  • Tzagoloff A, Barientos A, Neupert W and Herrmann JM. 2004. Atp10p assists assembly of Atp6p into the Fo unit of the yeast mitochondrial ATPase. J Biol Chem. 279, 19775-19780
  • Funes S, Nargang FE, Neupert W and Herrmann JM. 2004. The Oxa2 protein of Neurospora crassa plays a critical role in the biogenesis of cytochrome oxidase and defines a ubiquitous subbranch of the Oxa1/YidC/Alb3 protein family. Mol Biol Cell. 15, 1853-1861
  • Herrmann JM and Bonnefoy N. 2004. Protein export across the inner membrane of mitochondria: The nature of translocated domains determines the dependence on the Oxa1 translocase. J Biol Chem. 279, 2507-2512


  • Szyrach G, Ott M, Bonnefoy N, Neupert W und Herrmann JM. 2003. Ribosome binding to the Oxa1 translocase facilitates cotranslational protein insertion in mitochondria. EMBO J. 22, 6448-6457
  • Lutz T, Neupert W and Herrmann JM. 2003. Import of small Tim proteins into the mitochondrial intermembrane space. EMBO J. 22, 4400-4408
  • Herrmann JM and Neupert W. 2003. Protein insertion into the inner membrane of mitochondria. IUBMB Life 55, 219-225
  • Sandmann T, Herrmann JM, Dengjel J, Schwarz H and Spang A. 2003. Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in S. cerevisiae. Mol Biol Cell 14, 3097-3113
  • Meier S and Herrmann JM. 2003. Quo vadis, Protein? Proteinsortierung in Mitochondrien. Bioforum 1-2/2003, 32-34
  • Herrmann JM. 2003. Converting bacteria to organelles: evolution of mitochondrial protein sorting. Trends in Microbiology 11, 74-79


  • Duby G, Foury F, Ramazotti A, Herrmann JM and Lutz T. 2002. A non-essential function for yeast frataxin in iron-sulfur cluster assembly. Hum Mol Genet. 11, 2635-2643
  • Baumann F, Neupert W and Herrmann JM. 2002. Insertion of bitopic membrane proteins into the inner membrane of mitochondria involves an export step from the matrix. J Biol Chem. 277, 21405-21413
  • Nargang FE, Preuss M, Neupert W and Herrmann JM. 2002. The homooligomeric Oxa1 protein forms an essential part of the mitochondrial export translocase in Neurospora crassa. J Biol Chem. 277, 12846-12853


  • Preuss M, Leonhard K, Neupert W and Herrmann JM. 2001. Mba1, a novel component of the mitochondrial protein export machinery of the yeast S. cerevisiae. J Cell Biol. 153, 1035-1045
  • Lutz T, Westermann B, Neupert W and Herrmann JM. 2001. The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria. J Mol Biol. 307, 815-825
  • Spang A, Herrmann JM, Hamamoto S and Schekman R. 2001. The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell. 12, 1035-1045
  • Herrmann JM, Westermann B and Neupert W. 2001. Analysis of protein-protein interactions in mitochondria by co-immunoprecipitation and chemical cross-linking. Methods Cell Biol. 65, 217-230
  • Westermann B, Herrmann JM and Neupert W. 2001. Analysis of mitochondrial translation products in vivo and in organello in yeast. Methods Cell Biol. 65, 429-438


  • Baumann F, Milisav E, Neupert W and Herrmann JM. 2000. Ecm10, a novel Hsp70 homolog in the mitochondrial matrix of the yeast Saccharomyces cerevisiae. FEBS Lett. 487, 307-312
  • Berger T, Brigl M, Herrmann JM, Vielhauer V, Luckow B, Schlöndorff D and Kretzler M. 2000. The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins. J Cell Sci. 113, 3603-3612
  • Herrmann JM and Neupert W. 2000. What fuels polypeptide translocation? An energetical view on mitochondrial protein sorting. Biochem Biophys Acta 1459, 331-338
  • Herrmann JM and Neupert W. 2000. Protein transport into mitochondria. Curr Opin Microbiol. 3, 210-214


  • Marzioch M, Henthorn JM, Hermann R, Wilson DY, Thomas JJM, Bergeron R, Solari CE and Rowley A. 1999. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Mol Biol Cell 10, 1923-1938
  • Herrmann JM, Malkus P and Schekman R. 1999. Out of the ER - outfitters, escorts and guides. Trends Cell Biol. 9, 5-7


  • Kuehn MJ, Herrmann JM and Schekman R. 1998. COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature 391, 187-190
  • Hell K, Herrmann JM, Pratje E, Neupert W and Stuart RA. 1998. Oxa1p, an essential component of the N-tail protein export machinery in mitochondria. Proc Natl Acad Sci USA. 95, 2250-2255


  • Hell K, Herrmann JM, Pratje E, Neupert W and Stuart RA. 1997. Oxa1p mediates the export of the N- and C-termini of pCoxII from the mitochondrial matrix to the intermembrane space. FEBS Lett. 418, 367-370
  • Herrmann JM, Neupert W and Stuart RA. 1997. Insertion into the mitochondrial inner membrane of a polytopic protein, the nuclear-encoded Oxa1p. EMBO J. 16, 2217-2226


  • Westermann, B, Gaume B, Herrmann JM, Neupert W and Schwarz E. 1996. Role of the mitochondrial DnaJ homolog, Mdj1p, as a chaperone for mitochondrially synthesized and imported proteins. Mol Cell Biol. 16, 7063-7071
  • Leonhardt K, Herrmann JM, Stuart SA, Mannhaupt G, Neupert W and Langer T. 1996. AAA proteases with catalytic sites on opposite membrane surfaces cooperate in the ATP-dependent degradation of inner membrane proteins in mitochondria. EMBO J. 15, 4218-4229


Herrmann JM, Koll H, Cook RA, Neupert W and Stuart RA. 1995. Topogenesis of cytochrome oxidase subunit II. Mechanisms of protein export from the mitochondrial matrix. J Biol Chem. 270, 27079-27068


  • Herrmann JM, Stuart RA, Craig EA and Neupert W. 1994. Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA. J Cell Biol. 127, 893-902
  • Herrmann JM, Fölsch H, Stuart RA and Neupert W. 1994. Isolation of yeast mitochondria and study of mitochondrial protein translation. In Cell Biology: A Laboratory Handbook, Volume 1 (Celis, D.E., ed) 538-544, Academic Press Inc., New York.


Fehler F, Herrmann JM, Saalmüller A, Mettenleiter TM and Keil GM. 1992. Glycoprotein IV of bovine herpes virus 1-expressing cell line complements and rescues a conditionally lethal viral mutant. J Virol. 66, 831-839

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